00188187

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Long-Term Survival for 10 Years of a Patient with Amyloidosis of the Gastro-lntestinal Tract : Improvement of Clinical Manifestations by Using Oral DMSO and Intravenous Hyperalimentation

English (英語)

Bulletin of allied medical sciences Kobe : BAMS (Kobe)

13

185-191

神戸大学医学部保健学科

1997-12-26

2006-09-12

本文ファイルは、国立情報学研究所CiNiiより提供されたものです。

At the age of 58, the patient started to recognize clinical manifestations of diarrhea and abdonimal pain. Unresponsive to glucocorticoid administration or sarazopyrin intake, a clinical diagnosis of nonspecific enterocolitis was made. However, a histological examination on a rectal biopsy introduced her an admission to the hospital obtaining a histological diagnosis of amyloid deposits. On admission, she was found to be poorly nourished and anemic. The skin was slightly edematous and abdominal surface was slightly distended. She had remarkable improvement under total parenteral nutrition with oral intake of dimethylsulfoxide (7.5 gm daily for a year and 3 gm daily for subsequent 3 years), observing clinical and laboratory findings. She has been well at home for the following 10 years, when she was found to have increased proteinuria and high blood urea nitrogen. Manual peritoneal dialysis started, 4 times a week at out-patient clinic. A total 10 years survival of gastro-intestinal amyloidosis in this patient was here in described.

Intravenous alimentation

紀要論文