The Japan-Multimodal Intervention Trial for Prevention of Dementia PRIME Tamba (J-MINT PRIME Tamba): Study protocol of a randomised controlled multi-domain intervention trial

Kumagai, Ryoko; Osaki, Tohmi; Oki, Yutaro; Murata, Shunsuke; Uchida, Kazuaki; Encho, Haruhi; Ono, Rei; Kowa, Hisatomo

https://hdl.handle.net/20.500.14094/0100476504

このアイテムのアクセス数:166件（2025-05-09 13:51 集計）

閲覧可能ファイル

ファイル	フォーマット	サイズ	閲覧回数	説明
0100476504 (fulltext)	pdf	431 KB	159

メタデータ

ファイル出力

メタデータID	0100476504
アクセス権	open access
出版タイプ	Version of Record
タイトル	The Japan-Multimodal Intervention Trial for Prevention of Dementia PRIME Tamba (J-MINT PRIME Tamba): Study protocol of a randomised controlled multi-domain intervention trial
著者	Kumagai, Ryoko ; Osaki, Tohmi ; Oki, Yutaro ; Murata, Shunsuke ; Uchida, Kazuaki ; Encho, Haruhi ; Ono, Rei ; Kowa, Hisatomo
著者名 Kumagai, Ryoko
著者ID A2648 KUID https://kuid-rm-web.ofc.kobe-u.ac.jp/search/detail?systemId=e4782e988831cba1520e17560c007669 著者名 Osaki, Tohmi 尾嵜, 遠見オサキ, トオミ所属機関名保健学研究科
著者ID A2818 研究者ID 1000040809240 KUID https://kuid-rm-web.ofc.kobe-u.ac.jp/search/detail?systemId=5e3fbb72700e55c2520e17560c007669 著者名 Oki, Yutaro 沖, 侑大郎オキ, ユウタロウ所属機関名保健学研究科
著者ID A2652 著者名 Murata, Shunsuke 村田, 峻輔ムラタ, シュンスケ所属機関名保健学研究科
著者名 Uchida, Kazuaki
著者名 Encho, Haruhi
著者ID A0082 研究者ID 1000050346243 KUID https://kuid-rm-web.ofc.kobe-u.ac.jp/search/detail?systemId=bd4fdd7a99211f9c520e17560c007669 著者名 Ono, Rei 小野, 玲オノ, レイ所属機関名保健学研究科
著者ID A0128 研究者ID 1000060396728 KUID https://kuid-rm-web.ofc.kobe-u.ac.jp/search/detail?systemId=4a427f6a812e8867520e17560c007669 著者名 Kowa, Hisatomo 古和, 久朋コワ, ヒサトモ所属機関名保健学研究科
言語	English (英語)
収録物名	Archives of Gerontology and Geriatrics
巻(号)	104
ページ	104803
出版者	Elsevier B.V.
刊行日	2023-01-01
公開日	2022-09-28
抄録	The Japan-Multimodal Intervention Trial for Prevention of Dementia PRIME Tamba (J-MINT PRIME Tamba) is a randomised controlled trial to prevent cognitive decline in community-dwelling cognitively ordinary older people at risk of dementia. Participants are aged 65–85 years living in a rural area in Japan, aware of very mild decline in cognitive function or abilities of activities of daily living, have at least one vascular risk (e.g. hypertension or diabetes), and have a Mini-Mental State Examination score of 24 or higher. Approximately 200 participants are randomly divided into two groups, with the intervention group receiving a multi-modal intervention, including lifestyle-related disease management, physical exercise, cognitive training, and nutritional counselling, over 18 months. The primary outcome is change in the composite score of seven neuropsychological tests, including the Free and Cued Selective Reminding Test, Logical Memory I and II subsets of the Wechsler Memory Scale-Revised, and Digit Symbol Substitution Test of the Wechsler Adult Intelligence Scale. In addition, changes in a wide range of other parameters such as physical function, blood test results, sleep, and frailty are also analysed as secondary outcomes. We believe that this study's results will contribute significantly to the development of dementia prevention measures in Japan. Clinical trial registration number: UMIN000041938
キーワード	Cognitive decline
	Multi-domain intervention
	Vascular risk management
	Physical exercise
	Cognitive training
	Nutritional counselling
カテゴリ	保健学研究科
カテゴリ	学術雑誌論文
権利	© 2022 The Authors. Published by Elsevier B.V.
権利	This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
関連情報	DOI https://doi.org/10.1016/j.archger.2022.104803

資源タイプ	journal article
ISSN	0167-4943　OPACで所蔵を検索　 CiNiiで学外所蔵を検索

閲覧可能ファイル

メタデータ

詳細を表示