神戸大学附属図書館デジタルアーカイブ
https://hdl.handle.net/20.500.14094/0100477315

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メタデータID
0100477315
アクセス権
open access
出版タイプ
Accepted Manuscript
タイトル
Risk of surgical failure and hemorrhagic complications associated with antithrombotic medication in glaucoma surgery
著者
Takano, Fumio ; Mori, Sotaro ; Okuda, Mina ; Murai, Yusuke ; Ueda, Kaori ; Sakamoto, Mari ; Kurimoto, Takuji ; Yamada-Nakanishi, Yuko ; Nakamura, Makoto
著者名
Takano, Fumio
著者名
Mori, Sotaro
著者名
Okuda, Mina
著者名
Murai, Yusuke
著者ID
A2426
研究者ID
1000070792232
KUID
https://kuid-rm-web.ofc.kobe-u.ac.jp/search/detail?systemId=121a64d967b801de520e17560c007669
著者名
Ueda, Kaori
上田, 香織
ウエダ, カオリ
所属機関名
医学部附属病院
著者ID
A2431
ORCID
0000-0003-0370-2190
KUID
https://kuid-rm-web.ofc.kobe-u.ac.jp/search/detail?systemId=e0fd31caf46bb45b520e17560c007669
著者名
Sakamoto, Mari
坂本, 麻里
サカモト, マリ
所属機関名
医学研究科
著者ID
A1535
研究者ID
1000050388815
著者名
Kurimoto, Takuji
栗本, 拓治
クリモト, タクジ
所属機関名
医学部附属病院
著者ID
A1365
研究者ID
1000000359861
KUID
https://kuid-rm-web.ofc.kobe-u.ac.jp/search/detail?systemId=d9c758f40b2218da520e17560c007669
著者名
Yamada-Nakanishi, Yuko
山田, 裕子
ヤマダ, ユウコ
所属機関名
医学研究科
著者ID
A0882
研究者ID
1000080273788
KUID
https://kuid-rm-web.ofc.kobe-u.ac.jp/search/detail?systemId=82142348522a81ad520e17560c007669
著者名
Nakamura, Makoto
中村, 誠
ナカムラ, マコト
所属機関名
医学研究科
言語
English (英語)
収録物名
Graefe's Archive for Clinical and Experimental Ophthalmology
巻(号)
260(11)
ページ
3607-3615
出版者
Springer
刊行日
2022-11
公開日
2023-07-01
抄録
Purpose: The purpose of this retrospective study was to determine the extent to which the use of antithrombotic drugs during glaucoma surgery contributes to surgical failure and postsurgical hemorrhagic complications. Methods: Glaucoma surgeries were categorized into three groups: trabeculotomy (TLO), trabeculectomy (TLE), and long-Tube shunt surgery (Tube). At 1 year after surgery, the following criteria for surgical success were met: intraocular pressure (IOP) in the 5–21-mmHg range, IOP reduction of at least 20% from the preoperative level, and no additional glaucoma surgeries. We compared the percentages of the success rates and hemorrhagic complications between antithrombotic medication experiencers and non-experiencers. Furthermore, we adjusted the preoperative factors between the two groups using a propensity score analysis in TLO and TLE surgeries. Results: A total of 910 glaucoma surgeries were included, with TLO, TLE, and Tube accounting for 353, 444, and 113 surgeries, respectively. Preoperative antithrombotic medications were administered to 149 patients in all glaucoma surgeries: 37 patients used only anticoagulants, 102 used only antiplatelets, and 10 used both. There was no significant difference in the success rates of any of the procedures. The hemorrhagic complications (hyphema and vitreous hemorrhage rate) were significantly higher in the patients who underwent TLE and Tube. The surgical success rates of TLO and TLE were not significantly different after the two groups were matched by propensity score. Conclusion: The perioperative use of antithrombotic drugs did not affect success for any of the procedures. However, it increased early postoperative hemorrhagic complications for TLE and Tube.
キーワード
Glaucoma surgery
Antithrombotic medication
Surgical failure
Hemorrhagic complication
カテゴリ
医学研究科
医学部附属病院
学術雑誌論文
権利
This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature's AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: https://doi.org/10.1007/s00417-022-05719-1
関連情報
DOI
https://doi.org/10.1007/s00417-022-05719-1