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https://hdl.handle.net/20.500.14094/0100483350

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メタデータID
0100483350
アクセス権
open access
出版タイプ
Version of Record
タイトル
Effects of Mobilization within 72 h of ICU Admission in Critically Ill Patients: An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials
著者
Matsuoka, Ayaka ; Yoshihiro, Shodai ; Shida, Haruka ; Aikawa, Gen ; Fujinami, Yoshihisa ; Kawamura, Yusuke ; Nakanishi, Nobuto ; Shimizu, Motohiro ; Watanabe, Shinichi ; Sugimoto, Kensuke ; Taito, Shunsuke ; Inoue, Shigeaki
著者名
Matsuoka, Ayaka
著者名
Yoshihiro, Shodai
著者名
Shida, Haruka
著者名
Aikawa, Gen
著者名
Fujinami, Yoshihisa
著者名
Kawamura, Yusuke
著者名
Nakanishi, Nobuto
著者名
Shimizu, Motohiro
著者名
Watanabe, Shinichi
著者名
Sugimoto, Kensuke
著者名
Taito, Shunsuke
著者ID
A2411
研究者ID
1000030582209
KUID
https://kuid-rm-web.ofc.kobe-u.ac.jp/search/detail?systemId=34321d03fcf61f45520e17560c007669
著者名
Inoue, Shigeaki
井上, 茂亮
イノウエ, シゲアキ
所属機関名
医学研究科
言語
English (英語)
収録物名
Journal of Clinical Medicine
巻(号)
12(18)
ページ
5888
出版者
MDPI
刊行日
2023-09
公開日
2023-10-12
抄録
Previous systematic review and meta-analysis indicates that rehabilitation within a week of intensive care unit (ICU) admission benefits physical function in critically ill patients. This updated systematic review and meta-analysis aim to clarify effects of initiating rehabilitation within 72 h of ICU admission on long-term physical, cognitive, and mental health. We systematically searched the MEDLINE, Cochrane Central Register of Controlled Trials, and Igaku Chuo Zasshi for randomized controlled trials (RCTs) between April 2019 and November 2022 to add to the previous review. Two investigators independently selected and extracted data. Pooled effect estimates for muscle strength, cognitive function, mental health after discharge, and adverse events were calculated. Evidence certainty was assessed via Grading of Recommendations, Assessment, Development, and Evaluations. Eleven RCTs were included in the meta-analysis. Early rehabilitation may improve muscle strength (three trials; standard mean difference [SMD], 0.16; 95% confidence interval [CI], −0.04–0.36) and cognitive function (two trials; SMD, 0.54; 95% CI, −0.13–1.20). Contrastingly, early mobilization showed limited impact on mental health or adverse events. In summary, initiating rehabilitation for critically ill patients within 72 h may improve physical and cognitive function to prevent post-intensive care syndrome without increasing adverse events. The effect on mental function remains uncertain.
キーワード
intensive care unit
post-intensive care syndrome
muscle strength
cognitive function
mental health
quality of life
activities of daily living
カテゴリ
医学研究科
学術雑誌論文
権利
© 2023 by the authors. Licensee MDPI, Basel, Switzerland.
CC license
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license
関連情報
DOI
https://doi.org/10.3390/jcm12185888