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YOLK SAC TUMOR IN THE CEREBELLUM : A CASE REPORT

English (英語)

The Kobe journal of the medical sciences

31(2)

63-72

1985-04

A 4-year and 7-month old boy with a cerebellar yolk sac tumor was treated with an enucleation of the tumor and post-operative irradiation. However, the titer of alpha-fetoprotein increased vigorously and a CT-scan showed an enhancing mass in the same primary location. He received the second operation by left hemi-cerebellectomy 6 months following the first operation. His clinical course is favorable until the age of 5 years and 3 months. Histological features revealed a typical yolk sac tumor with a reticular pattern with hyaline droplets in the stroma and the cytoplasm of tumor cells, and Schiller-Duval bodies like glomeruloid vessels. These hyaline droplets were positive in PAS and AFP staining. By transmission electron microscope, the droplets in the tumor cells were shown to be round dense bodies with a halo, less than 3 microns in diameter, with or without limiting membrane. Their cut mulberry like structure when microscope.

alpha-fetoprotein

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