0100489040

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CLINICAL AND LABORATORY EXAMINATIONS ON A CASE OF "HEMORRHAGIC FEVER" FOUND IN SURABAJA, INDONESIA, IN 1968

English (英語)

The Kobe journal of the medical sciences

16(4)

203-210

1970-12

In August 1968, a three-year-old native boy in the City of Surabaja, East Java, was found to have symptoms characteristic of "hemorrhagic fever" (HF), with sudden onset of high fever, vomiting, and diarrhea. Small petechiae were manifested on the extremities and face. Tourniquet test was strongly positive. The blood platelets were extremely decreased. Hepatomegaly and disturbance of liver functions were noted, but no jaundice was observed. Thereafter, a shock-like state appeared which lasted for two days. Fortunately the patient gained a complete and uneventful recovery by medical treatments. Serological tests indicated that the patient's hemagglutination-inhibition (HI) titers against dengue types 1, 2 and 4, as well as against Japanese encephalitis and yellow fever viruses were initially low and later elevated, showing especially a 16 times rise of titers against dengue type 2. Isolation of the virus from the patient's blood, however, was not unequivocal. Based on these data, and compared with previous descriptions on the HF syndromes found in Southeast Asian areas such as Manila, Bangkok and Singapore, the Surabaja case was diagnosed as HF which was presumably caused by infection of dengue type 2 virus. This is perhaps the first case clinical-virologically confirmed as HF in Indonesia.

Indonesia

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