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A STUDY ON THE ENDEMIC GOITER IN MADJALENGKA DISTRICT OF THE REPUBLIC OF INDONESIA

English (英語)

The Kobe journal of the medical sciences

13(3)

181-220

1967-09

The Kobe University School of Medicine and Kobe Medical College continued yearly medical survey in summer in Indonesia since 1964 in an attempt to promote mutual friendship between Japan and Indonesia through medicine. Between July and September 1966, we have conducted a medical survey and service on 812 patients in the mountain district of Madjalengka area, western part of Java including Nunuk, Tjibodas, Argalingga, Tjipulus, Kantjana, Madialengka districts in Indonesia. Goiter was detected in 185 (22. 7%) among them. Each district showed a variation in the incidence of goiter even within the same part of the island. Goiter patients were frequently found in Nunuk (29.3%), Tjibodas (66. 7%), and Argalingga district (38.2%), while scarcely any goiter was detected in Tjipulus, Kantjana, and Madjalengka districts. Most of the goiter showed nodular adenomatous enlargement upon palpation, and an increase in size was noted with advancing age. Although no significant difference was found in the occurrence of goiter between males and females, goiter was frequently seen agmong ages of 20 and 50 years. In 22.1% of the goiter patients, other member of the family also had goiter. From the functional aspects, most of the goiter belonged to euthyroid goiter, with the exception of a few cases with suspected hyper- or hypothyroidism. In 11 of the 181 cases malignant transformation of goiter into cancer was suspected. As for the cause of such endemic goiter, living environment of the district appears to be most important, iodine deficiency being one of them, though a definite conclusion has not been reached at present.

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