0100489422

open access

Accepted Manuscript

Catalytic Approaches to the Halogen Dance Reaction for Molecular Editing

English (英語)

ChemCatChem

16(14)

e202400408

John Wiley & Sons

2024-07-22

2025-04-24

Published Online: 2024-04-24

Transposition reactions, i. e., switching the position of functional groups, are a powerful tool for molecular editing. The transposition of a halogen atom attached to an aromatic ring, referred to as the halogen dance reaction, has great potential in the fields of pharmaceuticals, agrochemicals, natural products, and functional materials. However, the substrate scope of this reaction is limited owing to the intrinsic difficulty in facilitating multiple catalytic cycles involving several aryllithium species. In this concept paper, recent advances in halogen dance catalysis that have expanded the substrate scope of this reaction are highlighted.

Organocatalysis

学術雑誌論文

This is the peer reviewed version of the following article: [K. Inoue, K. Okano, ChemCatChem 2024, 16, e202400408.], which has been published in final form at [https://doi.org/10.1002/cctc.202400408]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.