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https://hdl.handle.net/20.500.14094/0100495518

このアイテムのアクセス数:31件（2025-06-25 14:00 集計）

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メタデータID
0100495518
アクセス権
open access
出版タイプ
Accepted Manuscript
タイトル
Gait speed, life-space mobility and mild cognitive impairment in patients with coronary artery disease
著者
Ishihara, Kodai ; Izawa, P. Kazuhiro ; Kitamura, Masahiro ; Ogawa, Masato ; Shimogai, Takayuki ; Kanejima, Yuji ; Morisawa, Tomoyuki ; Shimizu, Ikki
著者名
Ishihara, Kodai
著者ID
A1350
研究者ID
1000010736185
KUID
https://kuid-rm-web.ofc.kobe-u.ac.jp/search/detail.html?systemId=3330637c7f4d6307520e17560c007669
著者名
Izawa, P. Kazuhiro
井澤, 和大
イザワ, カズヒロ
所属機関名
保健学研究科
著者名
Kitamura, Masahiro
著者名
Ogawa, Masato
著者名
Shimogai, Takayuki
著者名
Kanejima, Yuji
著者名
Morisawa, Tomoyuki
著者名
Shimizu, Ikki
言語
English (英語)
収録物名
Heart and Vessels
巻(号)
36(2)
ページ
147-154
出版者
Springer Nature
刊行日
2021-02
公開日
2025-04-08
抄録
Slow gait speed and restricted life-space mobility predict cognitive decline and dementia in healthy older adults, yet the relation between gait speed or life-space mobility and cognitive function remains poorly understood in patients with coronary artery disease (CAD). We, therefore, examined the following relations: that between gait speed and cognitive function, and mild cognitive impairment (MCI) and that between life-space mobility and cognitive function, and MCI. We conducted a cross-sectional study of 240 non-dementia patients who met the study criteria from 2132 consecutive CAD patients. MCI was estimated with the Japanese version of the Montreal Cognitive Assessment (MoCA-J). Gait speed was measured to perform gait trials at the patients’ usual walking pace, and life-space mobility was evaluated using the Life-Space Assessment (LSA). We investigated the relation between gait speed or life-space mobility and cognitive function by Pearson correlation analysis, whereas multivariable logistic regression analysis was conducted for detecting MCI. Gait speed and LSA scores were positively associated with the MoCA-J score (r = 0.54, p < 0.001 and r = 0.44, p < 0.001, respectively), and both were independently associated with MCI in the multivariable logistic regression analysis (odds ratio 0.007, p < 0.001, and odds ratio 0.98, p = 0.038, respectively). Cognitive impairment can be easily detected by assessment of gait speed and life-space mobility. Interventions to improve gait speed and life-space mobility may lead to the improvement of cognitive function and MCI in patients with CAD.
キーワード
Cognitive function
Coronary artery disease
Gait speed
Life-space mobility
Mild cognitive impairment
カテゴリ
保健学研究科
学術雑誌論文
権利
This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature's AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: https://doi.org/10.1007/s00380-020-01677-y
関連情報
DOI
https://doi.org/10.1007/s00380-020-01677-y
PMID
32770346