0100495626

open access

Version of Record

Antimicrobial and antiviral activities and reaction mechanisms of an organic photocatalyst upon visible-light irradiation

English (英語)

Research on Chemical Intermediates

51(5)

2591-2604

Springer Nature

2025-05

2025-04-22

Organic photocatalyst 9,10-dicyanoanthracene (CN-anthracene) has been demonstrated to exhibit antimicrobial activity upon visible-light irradiation. By evaluating these dependencies, this research aims to clarify the underlying mechanisms of its photocatalytic action and provide insights into its practical applications in diverse antimicrobial scenarios. This study examined the light and temperature dependence of the antimicrobial activity of CN-anthracene to further investigate its photocatalytic properties in detail. The antimicrobial activity was evaluated using the colony count method with Escherichia coli (E. coli) as the target organism. The results indicated that the antimicrobial rate increased with the light intensity and that the antimicrobial activity was above a certain level regardless of the temperature in the expected indoor temperature range. The antiviral activity of the photocatalyst was investigated using a median tissue culture infectious dose (TCID₅₀) assay. The results showed that the photocatalyst exhibited high viral activity against both enveloped and non-enveloped viruses. Furthermore, the presence of reactive oxygen species (·OH and ·O₂⁻), which are believed to play a critical role in the observed antibacterial and antiviral activities, was confirmed. These findings demonstrate that CN-anthracene exhibits high antibacterial and antiviral activities under visible light, highlighting its potential as a novel tool for combating infectious diseases.

9,10-Dicyanoanthracene

学術雑誌論文

This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder.