Risk Factors for Wound Dehiscence After Spinal Metastasis Surgery and a New Approach to Prevention—Curved Skin Incision

Miyazaki, Kunihiko; Kanda, Yutaro; Yurube, Takashi; Takeoka, Yoshiki; Tsujimoto, Takeru; Matsuo, Tomoya; Ryu, Masao; Kumagai, Naotoshi; Kuroshima, Kohei; Hiranaka, Yoshiaki; Kuroda, Ryosuke; Kakutani, Kenichiro

https://hdl.handle.net/20.500.14094/0100496590

このアイテムのアクセス数:110件（2026-04-02 03:07 集計）

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メタデータID	0100496590
アクセス権	open access
出版タイプ	Version of Record
タイトル	Risk Factors for Wound Dehiscence After Spinal Metastasis Surgery and a New Approach to Prevention—Curved Skin Incision
著者	Miyazaki, Kunihiko ; Kanda, Yutaro ; Yurube, Takashi ; Takeoka, Yoshiki ; Tsujimoto, Takeru ; Matsuo, Tomoya ; Ryu, Masao ; Kumagai, Naotoshi ; Kuroshima, Kohei ; Hiranaka, Yoshiaki ; Kuroda, Ryosuke ; Kakutani, Kenichiro
著者名 Miyazaki, Kunihiko
著者ID A3886 研究者ID 1000051010524 KUID https://kuid-rm-web.ofc.kobe-u.ac.jp/search/detail.html?systemId=90bc5271e38d75c2520e17560c007669 著者名 Kanda, Yutaro 神田, 裕太郎カンダ, ユウタロウ所属機関名医学部附属病院
著者ID A2131 研究者ID 1000010514648 KUID https://kuid-rm-web.ofc.kobe-u.ac.jp/search/detail.html?systemId=564b5b743f5a7d84520e17560c007669 著者名 Yurube, Takashi 由留部, 崇ユルベ, タカシ所属機関名医学部附属病院
著者ID A3390 研究者ID 1000030943592 KUID https://kuid-rm-web.ofc.kobe-u.ac.jp/search/detail.html?systemId=4a9f37836e6eafb2520e17560c007669 著者名 Takeoka, Yoshiki 武岡, 由樹タケオカ, ヨシキ所属機関名医学研究科
著者名 Tsujimoto, Takeru
著者名 Matsuo, Tomoya
著者名 Ryu, Masao
著者名 Kumagai, Naotoshi
著者名 Kuroshima, Kohei
著者名 Hiranaka, Yoshiaki
著者ID A0783 研究者ID 1000080379362 KUID https://kuid-rm-web.ofc.kobe-u.ac.jp/search/detail.html?systemId=f51cbfc82378ae63520e17560c007669 著者名 Kuroda, Ryosuke 黒田, 良祐クロダ, リョウスケ所属機関名医学研究科
著者ID A1461 研究者ID 1000010533739 KUID https://kuid-rm-web.ofc.kobe-u.ac.jp/search/detail.html?systemId=3401110282b6c620520e17560c007669 著者名 Kakutani, Kenichiro 角谷, 賢一朗カクタニ, ケンイチロウ所属機関名医学研究科
言語	English (英語)
収録物名	Cancers
巻(号)	17(12)
ページ	1973
出版者	MDPI
刊行日	2025-06-13
公開日	2025-06-30
抄録	Background: Postoperative wound dehiscence is a major complication following spinal metastasis surgery, particularly in patients who receive preoperative radiotherapy or molecular-targeted therapy; however, preventive strategies remain limited. Objective: In this study, we aimed to identify the risk factors for postoperative wound dehiscence and evaluate the clinical utility of a novel curved skin incision (CSI) technique, designed to avoid irradiated areas, in comparison with the conventional midline incision (MI) technique. Methods: Logistic regression analysis was conducted on 107 patients who underwent MI between 2013 and 2018. Based on the results, we developed the CSI technique. Propensity score matching was performed to compare postoperative wound dehiscence in 29 matched pairs of patients treated with either CSI or MI from 2019 to 2021. Results: Preoperative radiotherapy and molecular-targeted therapy were found to be significant risk factors for wound dehiscence. CSI, which circumvents irradiated skin, was associated with a substantially lower rate of wound dehiscence than MI. Conclusions: The CSI technique offers a simple, reproducible, and effective surgical approach to reduce postoperative wound complications in high-risk patients. Its clinical benefit, especially for those with prior radiotherapy, suggests that it may serve as a valuable addition to standard spinal metastasis surgery.
キーワード	curved skin incision
	midline skin incision
	spinal metastasis
	wound dehiscence
	propensity score matching
	radiotherapy
カテゴリ	医学研究科
	医学部附属病院
	学術雑誌論文
権利	© 2025 by the authors. Licensee MDPI, Basel, Switzerland.
権利	This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license
関連情報	DOI https://doi.org/10.3390/cancers17121973
関連情報	PMID 40563623

資源タイプ	journal article
eISSN	2072-6694　OPACで所蔵を検索　 CiNiiで学外所蔵を検索

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