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https://doi.org/10.24546/81010551

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メタデータID
81010551
アクセス権
open access
出版タイプ
Version of Record
タイトル
Potential of Coffee Fruit Extract and Quinic Acid on Adipogenesis and Lipolysis in 3T3-L1 Adipocytes
著者
Duangjai, Acharaporn ; Nuengchamnong, Nitra ; Suphrom, Nungruthai ; Trisat, Kanittaporn ; Limpeanchob, Nanteetip ; Saokaew, Surasak
著者名
Duangjai, Acharaporn
著者名
Nuengchamnong, Nitra
著者名
Suphrom, Nungruthai
著者名
Trisat, Kanittaporn
著者名
Limpeanchob, Nanteetip
著者名
Saokaew, Surasak
言語
English (英語)
収録物名
The Kobe journal of the medical sciences
巻(号)
64(3)
ページ
84-92
出版者
神戸大学医学部
Kobe University School of Medicine
刊行日
2018
公開日
2018-10-22
抄録
This study was to assess the impact of different colors of coffee fruit (green, yellow and red) on adipogenesis and/or lipolysis using 3T3-L1 adipocytes. Characterization of chemical onstituents in different colors of coffee fruit extracts was determined by ESI-Q-TOF-MS. The cytotoxicity of the extracts in 3T3-L1 preadipocytes were evaluated by MTT assay. Oil-red O staining and amount of glycerol released in 3T3-L1 adipocytes were measured for lipid accumulation and lipolysis activity. All coffee fruit extracts displayed similar chromatographic profiles by chlorogenic acid > caffeoylquinic acid > caffeic acid. Different colors of raw coffee fruit possessed inhibitory adipogenesis activity in 3T3-L1 adipocytes, especially CRD decreased lipid accumulation approximately 47%. Furthermore, all extracts except CYF and their major compounds (malic, quinic, and chlorogenic acid) increased glycerol release. Our data suggest that different colors of coffee fruit extract have possessed anti-adipogenic and lipolytic properties and may contribute to the anti-obesity effects.
カテゴリ
The Kobe journal of the medical sciences ＞ 64巻 ＞ 64巻3号（2018）
紀要論文
関連情報
URI
http://www.med.kobe-u.ac.jp/journal/contents.html