神戸大学附属図書館デジタルアーカイブ
https://hdl.handle.net/20.500.14094/90005599

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メタデータID
90005599
アクセス権
open access
出版タイプ
Version of Record
タイトル
A comparison of the resection rate for cold and hot snare polypectomy for 4-9 mm colorectal polyps: a multicentre randomised controlled trial (CRESCENT study)
著者
Kawamura, Takuji ; Takeuchi, Yoji ; Asai, Satoshi ; Yokota, Isao ; Akamine, Eisuke ; Kato, Minoru ; Akamatsu, Takuji ; Tada, Kazuhiro ; Komeda, Yoriaki ; Iwatate, Mineo ; Kawakami, Ken ; Nishikawa, Michiko ; Watanabe, Daisuke ; Yamauchi, Atsushi ; Fukata, Norimasa ; Shimatani, Masaaki ; Ooi, Makoto ; Fujita, Koichi ; Sano, Yasushi ; Kashida, Hiroshi ; Hirose, Satoru ; Iwagami, Hiroyoshi ; Uedo, Noriya ; Teramukai, Satoshi ; Tanaka, Kiyohito
著者名
Kawamura, Takuji
著者名
Takeuchi, Yoji
著者名
Asai, Satoshi
著者名
Yokota, Isao
著者名
Akamine, Eisuke
著者名
Kato, Minoru
著者名
Akamatsu, Takuji
著者名
Tada, Kazuhiro
著者名
Komeda, Yoriaki
著者名
Iwatate, Mineo
著者名
Kawakami, Ken
著者名
Nishikawa, Michiko
著者名
Watanabe, Daisuke
著者名
Yamauchi, Atsushi
著者名
Fukata, Norimasa
著者名
Shimatani, Masaaki
著者ID
A0841
研究者ID
1000070448174
KUID
https://kuid-rm-web.ofc.kobe-u.ac.jp/search/detail?systemId=9bdf7d44129147d6520e17560c007669
著者名
Ooi, Makoto
大井, 充
オオイ, マコト
所属機関名
医学研究科
著者名
Fujita, Koichi
著者名
Sano, Yasushi
著者名
Kashida, Hiroshi
著者名
Hirose, Satoru
著者名
Iwagami, Hiroyoshi
著者名
Uedo, Noriya
著者名
Teramukai, Satoshi
著者名
Tanaka, Kiyohito
言語
English (英語)
収録物名
Gut
巻(号)
67(11)
ページ
1950-1957
出版者
BMJ Publishing Group
刊行日
2018-11
公開日
2019-02-20
抄録
Objective To investigate the success rate of cold snare polypectomy (CSP) for complete resection of 4–9 mm colorectal adenomatous polyps compared with that of hot snare polypectomy (HSP). Design A prospective, multicentre, randomised controlled, parallel, non-inferiority trial conducted in 12 Japanese endoscopy units. Endoscopically diagnosed sessile adenomatous polyps, 4–9 mm in size, were randomly assigned to the CSP or HSP group. After complete removal of the polyp using the allocated technique, biopsy specimens from the resection margin after polypectomy were obtained. The primary endpoint was the complete resection rate, defined as no evidence of adenomatous tissue in the biopsied specimens, among all pathologically confirmed adenomatous polyps. Results A total of 796 eligible polyps were detected in 538 of 912 patients screened for eligibility between September 2015 and August 2016. The complete resection rate for CSP was 98.2% compared with 97.4% for HSP. The non-inferiority of CSP for complete resection compared with HSP was confirmed by the +0.8% (90% CI −1.0 to 2.7) complete resection rate (non-inferiority p<0.0001). Postoperative bleeding requiring endoscopic haemostasis occurred only in the HSP group (0.5%, 2 of 402 polyps). Conclusions The complete resection rate for CSP is not inferior to that for HSP. CSP can be one of the standard techniques for 4–9 mm colorectal polyps. (Study registration: UMIN000018328)
カテゴリ
医学研究科
学術雑誌論文
権利
© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.
CC license
This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
関連情報
DOI
https://doi.org/10.1136/gutjnl-2017-314215