90006334

open access

Accepted Manuscript

Synthesis of Arylamines via Non‐Aerobic Dehydrogenation Using a Palladium/Carbon‐Ethylene System

English (英語)

Advanced Synthesis & Catalysis

360(17)

3297-3305

Wiley

2018-09-03

2019-10-01

This is the peer reviewed version of the following article: [Shimomoto, Yuya, Ryosuke Matsubara, and Masahiko Hayashi. Synthesis of Arylamines via Non‐Aerobic Dehydrogenation Using a Palladium/Carbon‐Ethylene System. Advanced Synthesis & Catalysis 360(17) 3297-3305.], which has been published in final form at https://doi.org/10.1002/adsc.201800504. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.

The reaction of cyclohexanones with amines proceeded under an ethylene atmosphere in the presence of a catalytic amount of palladium/carbon to afford a variety of arylamines in good to high yields. The present reaction was carried out under completely non‐aerobic conditions, and which is in contrast with the previously reported aerobic system. has wide applicability affording a variety of aromatic amines, and co‐product of the reaction is only gaseous ethane. Thus, this method is environmentally friendly. This protocol was applied intramolecularly to provide a novel method for the construction of quinoline and isoquinoline compounds.

Amination

学術雑誌論文