A novel type of regulatory protein for the GDP/GTP exchange reaction of rho p21, a ras p21-like small GTP-binding protein, in rabbit intestine.

https://hdl.handle.net/20.500.14094/E0034062

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38-2_117-134 (fulltext)	pdf	890 KB	25

メタデータID	E0034062
アクセス権	open access
出版タイプ	Version of Record
タイトル	A novel type of regulatory protein for the GDP/GTP exchange reaction of rho p21, a ras p21-like small GTP-binding protein, in rabbit intestine.
タイトル	A novel type of regulatory protein for the GDP/GTP exchange reaction of rho p21, a ras p21-like small GTP-binding protein, in rabbit intestine.
著者	著者名 Ohga, N
言語	English (英語)
収録物名	The Kobe journal of the medical sciences
巻(号)	38(2)
ページ	117-134
刊行日	1992
抄録	A novel regulatory protein for rho p21, a ras p21-like GTP-binding protein (G protein), was purified from the cytosol fraction of rabbit intestine. This protein, designated as rho GDP dissociation inhibitor (GDI), regulated the GDP/GTP exchange reaction of rho p21 by inhibiting the dissociation of GDP from and subsequent binding of GTP to it. rho GDI did not affect the GTPase activity of rho p21. rho GDI formed a complex with the GDP-bound form of rho p21 but not the GTP-bound form. rho GDI was inactive for other small G proteins including ras p21, smg p21 and smg p25A. These results indicate that rho GDI is a novel type of regulatory protein for the GDP/GTP exchange reaction of rho p21.
カテゴリ	The Kobe journal of the medical sciences ＞ 38巻＞ 38巻2号（1992）
カテゴリ	紀要論文

資源タイプ	departmental bulletin paper
ISSN	0023-2513　OPACで所蔵を検索　 CiNiiで学外所蔵を検索
NCID	AA00711740　OPACで所蔵を検索　 CiNiiで表示